
Antioxidant Serum · $$$
C E Ferulic
SkinCeuticals
See reviewsThe benchmark antioxidant serum: 15% L-ascorbic acid with vitamin E and ferulic acid, where ferulic stabilizes the vitamins and roughly doubles photoprotection.
- Best for
- Mature skin
- Price
- $$$
- Targets
- AgingBrighteningProtectionDark Spots
- Key actives
- Vitamin C (L-Ascorbic Acid), Hyaluronic Acid, Glycerin, Panthenol (Pro-Vitamin B5), Vitamin E (Tocopherol), Ferulic Acid
Benefits
- Neutralizes UV free radicals to prevent photoaging
- Brightens and firms with 15% L-ascorbic acid
- Ferulic acid stabilizes the C+E complex and boosts protection
Key ingredients explained
Vitamin C (L-Ascorbic Acid)
AntioxidantAs listed: L-Ascorbic Acid
A potent antioxidant that neutralizes UV-generated free radicals and acts as an essential cofactor for the enzymes that synthesize and stabilize collagen; it also inhibits tyrosinase to reduce melanin. The result is brighter, firmer, more even skin.
In the guideHyaluronic Acid
HumectantAs listed: Sodium Hyaluronate
A glycosaminoglycan humectant that binds large amounts of water; high-molecular-weight forms sit on the surface as a hydrating film, low-molecular-weight forms penetrate the stratum corneum. Because it is a humectant, in dry air it can pull water from deeper skin — so apply to damp skin and seal it.
In the guideGlycerin
HumectantA small humectant that attracts and holds water in the stratum corneum, delivered into the epidermis partly via aquaporin-3. It raises hydration, improves plasticity and desquamation, and supports barrier recovery — one of the best-evidenced moisturizing agents.
In the guidePanthenol (Pro-Vitamin B5)
SoothingAs listed: Panthenol
The stable analog of vitamin B5, converted in skin to pantothenic acid. As a humectant it improves hydration and lowers water loss, while soothing irritation, reducing erythema, and supporting barrier repair and re-epithelialization.
In the guideVitamin E (Tocopherol)
AntioxidantAs listed: Alpha Tocopherol
A fat-soluble antioxidant that neutralizes UV-generated free radicals and prevents lipid peroxidation and oxidative photoaging. It also moisturizes the stratum corneum and has anti-inflammatory activity — and works best alongside vitamin C.
In the guideFerulic Acid
AntioxidantA plant-derived phenolic antioxidant that neutralizes free radicals and, critically, stabilizes vitamins C and E in formulation. Added to a 15% vitamin C + 1% vitamin E solution it roughly doubles photoprotection against solar-simulated UV — the classic 'Duke' antioxidant complex.
In the guideFull ingredient list
Highlighted ingredients are explained above.
How to use
- 01Apply 4-5 drops to clean, dry skin each morning.
- 02Follow with moisturizer and SPF.
- 03Store away from light and heat.
Warnings
- May tingle initially.
- Discard if it turns dark amber (oxidized).
Expert summary
The original C E Ferulic and still the reference antioxidant serum; the ferulic-stabilized 15% L-ascorbic acid + vitamin E trio is the best-evidenced daytime photoprotective combo.
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